This study investigates the effect of computer based individualistic and cooperative learning strategy on achievement in chemistry in relation to scientific creativity. The sample of 216 students was drawn from IXth class taken from five different schools of Chandigarh affiliated to Central Board of Secondary Education Board, New Delhi. Computer based individualistic and cooperative learning was prepared and implemented to the experimental groups after pre- testing and gain scores were computed after post-test for all the students. The data was collected with the help of Scientific Creativity Test by Kalra (1993). The data obtained were analyzed statistically with the help of mean, standard deviation and analysis of variance. An analysis of variance (2×2) was used to arrive at the following conclusions: (i) The achievement of group taught through computer based cooperative learning was found significantly higher than that of group taught through computer based individualistic learning, (ii) Significant difference was found in scores of low and high scientific creativity groups of students in chemistry. (iii) No significant interaction effect was found between teaching strategies and scientific creativity on achievement in chemistry.